Minneapolis, MN (Sports Network) - Alexei Ramirez went 3-for-4 with a home run and three RBI to carry the Chicago White Sox past the Minnesota Twins, 5-2, in the finale of a four-game series at Target Field. Avisail Garcia doubled twice, scored a run and knocked in another, and Hector Santiago (4-7) earned his first win in nearly two months by limiting the Twins to two runs -- one earned -- on nine hits over six quality innings. Chicago won the final three games in the set, in part because Minnesota went 2-for-18 with runners in scoring position while squandering 12 baserunners on Sunday. Samuel Deduno (7-7) was charged with all five runs on eight hits over five innings for the Twins, who have dropped five of their last six games. Deduno plunked three hitters in the first three innings, and the first two wound up scoring. Gordon Beckham was hit in the first frame, took second on a balk and scored on Ramirezs single through the middle. Two innings later, Alejandro De Aza was hit in the foot and later scored on a double from Ramirez, who raced around for a 3-1 White Sox lead on Garcias two-bagger. Minnesota got its first run in the second inning when Trevor Plouffe doubled, advanced to third on an error and was pushed across on an Oswaldo Arcia groundout. The Twins added another in the third on Josh Willinghams RBI double, but Willingham was tagged out at home when he tried scoring on a wild pitch. Ramirez continued his big day with a leadoff blast to left field in the fifth, and Jeff Keppinger made it a 5-2 game with a two-out, run-scoring single later in the inning. Matt Lindstrom threw two innings of relief behind Santiago, and Addison Reed closed it out in the ninth for his 31st save. Game Notes The White Sox won three straight games on the road for the first time since taking four in a row from May 14-17 ... Santiago was 0-2 over his previous eight starts despite a minuscule 3.06 ERA. 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BOSTON -- David Ortiz celebrated two milestones on one hit and the Boston Red Sox survived two very close calls.Ortizs solo homer in the fifth inning Friday night was his 2,000th hit with Boston and 522nd career home run, moving into sole possession of 19th place on baseballs all-time list and breaking a tie he held with a trio of Hall of Famers including Red Sox great Ted Williams.The man did it all, Ortiz said of Williams after Bostons 5-4 win over the Los Angeles Angels on Friday night.Ortiz and Mookie Betts had three hits apiece for the Red Sox, who held on after a taking a 5-0 lead and handed the Angels their fourth straight loss and 10th in 11 games. Brock Holt had two doubles in his return to the lineup after missing more than a month with a concussion.C.J. Cron hit a grand slam for the Angels, who lost yet another game and a crucial ninth-inning challenge.Los Angeles nearly scored the tying run in the ninth but Mike Trout had to stop at third on Daniel Navas ground-rule double down the right-field line that bounced over the short wall. The Angels challenged, saying a fan touched the ball while it was still in play, but after a brief video review the call on the field stood.I dont know what theyre looking at in New York, but that ball is absolutely in the field of play when that fan touches it, Angels manager Mike Scioscia said. Absolutely. Its a joke.Craig Kimbrel finished up for his 17th save. Knuckleballer Steven Wright (9-5) got the win despite struggling with his control when the rain got heavy in the sixth. The rain delayed the game for 1 hour, 35 minutes.The Angels had the potential tying run on third in the eighth when Johnny Giavotella tripled to left-center with one out. The Angels tried getting him home with a safety squeeze that reliever Koji Uehara foiled with a great defensive play. Uehara scooped up Carlos Perezs bunt and flipped the ball with his glove to Christian Vazquez in time to tag Giavotella at the plate.Key play that takes you back to spring training, Boston manager John Farrell said. Thats something you do repetitively for 45 plus days and it showed up to be a pivotal play.Ortiz hadnt homered since tying Williams, Willie McCovey and Frank Thomas on June 17 against Seattle.dddddddddddd. Ortiz broke the tie with a line drive to right to put Boston up 3-0 in the fifth.Jackie Bradley Jr. followed with a single and scored on a double by Holt, who scored on a single by Vazquez to put Boston up 5-0.The rain started after Ortizs homer and was falling steadily by the top of the sixth, when Wrights shutout bid unraveled quickly. The knuckleballer struggled in the weather and the Angels loaded the bases with nobody out for Cron, who drove a 3-2 pitch over the Green Monster.Just looking for a pitch in the zone and I think I got it, Cron said. Its cool. Any first in this league is awesome.That was all for Wright, who allowed four runs on eight hits, walked three and struck out three.Jhoulys Chacin (2-5) allowed five runs on 12 hits in just 4 2/3 innings.NEXT UPNow alone at 19th on the all-time home run list, Ortiz trails No. 18 Jimmie Foxx (534) by a dozen and Mickey Mantle (536) for 17th. Ortiz, who is planning to retire at the end of the season, said he isnt looking at his statistics.One day I will, but right now I dont have time, he said.GOOD KIDBoston RF Beets had a much lighter outlook on Navas ground-rule double and the young fan who touched the ball.I think that ball was going to come back in play and obviously Trout is probably going to score on that ball, Betts said. Fortunately, he has pretty good hand eye coordination.TRAINERS ROOMAngels: LHP Andrew Heaney (torn ulnar collateral ligament) underwent Tommy John surgery in Los Angeles, likely sidelining him until the 2018 season.Red Sox: Holt was activated and start in left field, his first game since going on the concussion DL as of May 19. Holt had one of the defensive plays of the night in the fourth when he threw out Cron at second as he tried to stretch a line drive into a double.UP NEXTAngels: LHP Hector Santiago (4-4, 5.27) returns after getting tagged for six runs on seven hits and walks in a no-decision Sunday against Oakland.Red Sox: RHP Clay Buchholz (3-8, 5.90) is 0-2 in his return to the rotation after spending a few weeks in the bullpen. ' ' '